“A karyotyping is a process of preparing, arranging, categorizing chromosomes using cell culture technique.”
What is Karyotyping?- Definition, Steps, Process, and Advantages Read More »
A single copy of the Y chromosome, dosage-sensitive gene sets and lack of recombination event may result in a genetic degeneration timely on the Y chromosome, possibly going extinct in the future, researchers suggest. Related article: Are YY Chromosomes Possible? The question on the existence of the Y chromosome parted scientific fraternity into separate opinions,
Is the Y chromosome really disappearing- let’s findout a scientific answer Read More »
5p deletion syndrome also known as cri du chat syndrome occurs by a deletion on the p arm of chromosome 5, patients cry like a cat. Chromosome deletion occurs when some random events part some portion of the chromosome. The portion usually is huge having 10 to 1000 vital and important genes; deletion results in
5p deletion syndrome: Why do they cry like a cat? Read More »
Chromosome number 2 is among the 23 pairs of the human chromosome, a submetacentric chromosome with a length of 242, 193,529 bp in length having approximately 1767 coding genes. Present in a pair, the present set of chromosomes possesses a total of 8% of genomic DNA having 242 million bp DNA sequences on it. The
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Metaphase chromosomes are often known as metaphase plates or “meta’s” only in technical terms, have significant importance in genetic research, especially in cytogenetics and karyotyping studies. Techniques like conventional karyotyping, FISH- fluorescence in situ hybridization and SKY highly rely on metaphases. And therefore good, well-separated and sharper metaphases have been the objective first achieved. Although
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Any diagnostic reports that indicate to us regarding the problem with genetics and chromosomes the first and foremost thing that comes to our mind is the question asked above: are they permanent or temporary? Is it curable? How long is it going to stay in the body? Is it like any other disease or infection?
Are Chromosomal/ karyotyping Abnormalities Permanent or Temporary? Read More »
The 3q29 deletion syndrome occurs by deletion of some portion from the q arm of chromosome 3 results in phenotypic alterations. Chromosome 3 is the largest metacentric chromosome, comprises 200 million base pairs which represent 6.5% of total genomic content. Deletions are chromosome defects that occur when a part of a chromosome from either of
Investigating a Karyotype of 3q29 Microdeletion Syndrome Read More »
Karyotyping is a common clinical genetic technique to observe and investigate chromosomes. Scientists using the technique for a long time, though not less known. The karyotyping technique is now common for prenatal testing, fetal chromosome testing and to rule out other pregnancy-related problems and chromosomal aberrations. It is very important for couples who are going
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The dicentric chromosome is a highly uncommon event that occurs in the genome which causes genomic instability and cancer. We have written many articles on common chromosome aberrations or chromosomal abnormalities such as a change in number, deletion, duplication and translocation. These are common, studied well and can be identified easily using the conventional karyotyping
What is a Dicentric Chromosome?- Definition, Cause, Consequences Read More »
Double monosomy is the aberrant chromosomal condition commonly found in the plant genome but so rare in the human genome. Chromosomal aberrations or defects we can say, are classified broadly into aneuploidies. The monosomy is a kind of aneuploidy in which a single chromosome from a pair is missing. Meaning, that instead of normal 46
What Disorders are caused by the Double Monosomy? Read More »
A ring chromosome is formed when the ends of the same chromosome fuse together and make a ring-like structure. Chromosome ring formation is associated with certain health-related conditions. Broad two categorize of chromosome aberrations or chromosome abnormalities are structural and numerical aberrations. When any event alters the structure of a chromosome greatly is referred to
What is Ring Chromosome?- Definition, Mechanism and Abnormalities Read More »
