What is Karyotyping?- Definition, Steps, Process, and Advantages
“A karyotyping is a process of preparing, arranging, categorizing chromosomes using cell culture technique.”
Is the Y chromosome really disappearing- let’s findout a scientific answer
A single copy of the Y chromosome, dosage-sensitive gene sets and lack of recombination event may result in a genetic degeneration timely on the Y chromosome, possibly going extinct in the future, researchers suggest. Related article: Are YY Chromosomes Possible? The question on the existence of the Y chromosome parted scientific fraternity into separate opinions, …
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5p deletion syndrome: Why do they cry like a cat?
5p deletion syndrome also known as cri du chat syndrome occurs by a deletion on the p arm of chromosome 5, patients cry like a cat. Chromosome deletion occurs when some random events part some portion of the chromosome. The portion usually is huge having 10 to 1000 vital and important genes; deletion results in …
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Chromosome 2: Genes, Abnormalities and Disorders
Chromosome number 2 is among the 23 pairs of the human chromosome, a submetacentric chromosome with a length of 242, 193,529 bp in length having approximately 1767 coding genes. Present in a pair, the present set of chromosomes possesses a total of 8% of genomic DNA having 242 million bp DNA sequences on it. The …
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Importance of Metaphase Chromosomes in Karyotyping
Metaphase chromosomes are often known as metaphase plates or “meta’s” only in technical terms, have significant importance in genetic research, especially in cytogenetics and karyotyping studies. Techniques like conventional karyotyping, FISH- fluorescence in situ hybridization and SKY highly rely on metaphases. And therefore good, well-separated and sharper metaphases have been the objective first achieved. Although …
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Are Chromosomal/ karyotyping Abnormalities Permanent or Temporary?
Any diagnostic reports that indicate to us regarding the problem with genetics and chromosomes the first and foremost thing that comes to our mind is the question asked above: are they permanent or temporary? Is it curable? How long is it going to stay in the body? Is it like any other disease or infection? …
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Investigating a Karyotype of 3q29 Microdeletion Syndrome
The 3q29 deletion syndrome occurs by deletion of some portion from the q arm of chromosome 3 results in phenotypic alterations. Chromosome 3 is the largest metacentric chromosome, comprises 200 million base pairs which represent 6.5% of total genomic content. Deletions are chromosome defects that occur when a part of a chromosome from either of …
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Common Clinical Karyotyping FAQs
Karyotyping is a common clinical genetic technique to observe and investigate chromosomes. Scientists using the technique for a long time, though not less known. The karyotyping technique is now common for prenatal testing, fetal chromosome testing and to rule out other pregnancy-related problems and chromosomal aberrations. It is very important for couples who are going …
What is a Dicentric Chromosome?- Definition, Cause, Consequences
The dicentric chromosome is a highly uncommon event that occurs in the genome which causes genomic instability and cancer. We have written many articles on common chromosome aberrations or chromosomal abnormalities such as a change in number, deletion, duplication and translocation. These are common, studied well and can be identified easily using the conventional karyotyping …
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