Karyotyping

Cell culture: Definition, types, media and examples

Cell Culture: Definition, Types, Media and Examples

“The cell culture media is a composition of nutrients like amino acids, carbohydrates, vitamins and other ingredients essential for the growth of cells in vitro.”  Culture allows scientists to learn more about cells and related things! The cell culture is an aseptic condition to isolate cells followed by growing them artificially, in vitro processes using …

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what is the role of macro photography in karyotyping?

What is the role of Macro photography in Cytogenetics?

Photography, especially the macro photography lens is commonly used to investigate smaller living organisms and objects like chromosomes or chromosome bands. Do you know? Wide-angle lens, portrait lens and macro lenses are three common lenses used for various types of photography.  Cytogenetic technique such as karyotyping and FISH requires state of the art microscopy set …

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Why Karyotyping is performed using Monocytes only?

Why Karyotyping is performed using Monocytes only?

Monocytes are a special type of bone marrow-derived leukocytes commonly cultured in karyotyping procedure.  Karyotyping is a type of cytogenetic technique used commonly for observing chromosomes. Its objective is to investigate chromosomes for finding abnormalities associated with different genetic conditions.  It’s a traditional yet popular and versatile technique, scientists use for encountering various defects and …

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Why only Sodium Heparin Tubes are used to collect Samples for Karyotyping?

Why only Sodium Heparin Tubes are used to collect Samples for Karyotyping?

Sodium heparin is the best anticoagulant agent that prevents coagulation of blood henceforth sodium heparin-containing tubes are commonly used for the sample collection for karyotyping.  A very important procedure in cytogenetics and genetics is sample collection. The quality of results relies on the quality and conditions of the sample. Biological sample collection required special treatment, …

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What is Chromosomal Translocation?- Definition, Mechanism and Types

When a part of chromosome breaks or is deleted and reinserted at another location on a chromosome is known as a chromosome translocation. Conventional karyotyping is a technique commonly employed to study translocations.  Any sudden change, alteration or undesirable alteration in a gene or chromosome might be harmful to our health. “Mutation” is a common …

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