September 2020

ISCN- International System for Human Chromosome Nomenclature for Karyotyping

ISCN- International System for Human Chromosome Nomenclature was developed to denote various chromosomal anomalies to make results conclusive universally.  The manual of denotation is based on the outcomes of 1977’s standing committee met in Stockholm.  Karyotyping is a manual process to perform as well as to make and interpret results. Unlike other techniques a vast …

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GTG-Banding (G-bands by Trypsin using Giemsa) for karyotyping

GTG banding also is known as the Giemsa-trypsin-Giemsa banding technique is employed during karyotyping to investigate chromosomes and chromosomal anomalies.  Chromosomal anomalies like structural aberrations or numerical aberrations are commonly encountered using different types of banding techniques. GTG banding, R-banding, NOR-banding and Q- banding are popular techniques used routinely.  However, the GTG banding technique used …

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