Karyotyping is a process of seeing chromosomes in order to know abnormalities related to it. The metaphase chromosomes are most separatable and visible. Abnormalities in DNA or chromosomes can cause severe mental, physical or developmental disabilities. In order to find out the alteration related to chromosomes, we have to perform the cytogenetic analysis while to […]
Which Cell Division Phase is Best for Karyotyping? Read More »
“Mitotic inhibitor halts cell division during karyotyping in order to get separated chromosomes. Colchicine is a common mitotic inhibitor used in cytogenetic techniques like karyotyping.” Cytogenetic techniques are used to study cell and related components. Karyotyping is a method used to analyze chromosomes during cell division hence consider as cytogenetic technique. To get good chromosomes
Colchicine- A Mitotic Inhibitor in Karyotyping Read More »
“Mitogens are lectins or other peptides that bind to the cell surface and induce mitotic activity and cell division.“ By using the MAPK- mitotic activated protein kinase, a signal transduction pathway induced by mitogens leads to mitosis. The mitogens are potent endogenous or exogenous agents facilitating cell division by increasing mitotic activity. But what is
What are Mitogens? How is it Important in Karyotyping? Read More »
A karyotype is prepared in order to study the abnormalities associated with it that are commonly known as chromosomal abnormalities or karyotyping abnormalities. Usually, karyotyping abnormalities are either structural or numerical, notably, here single base change or other smaller alteration related DNA can’t be encountered using the karyotyping. However, as we know we can count
20 Common karyotyping (or Chromosomal) Abnormalities Read More »
Edwards syndrome is a type of chromosomal or karyotype abnormality that occurs due to the imbalance of chromosome number. During 1960, John Hilton Edwards first described the signs and symptoms of Edwards syndrome. The present genetic or chromosomal aberration is often known as T18 or trisomy 18. The mechanism known as trisomy is responsible for
A karyotype of Edwards Syndrome- Explained Read More »
Using a combination of different colored probes every chromosome present in a genome can be visualized differently. Talk of the topic: In the present article, we are discussing a general introduction to karyotyping, what spectral karyotyping is, and what is its principle and how it works. Also in the last segment of this article, we
What is a Spectral Karyotyping (SKY)? Read More »
A karyotype of Patau syndrome is known as T13, is a trisomy of chromosome 13 and majorly associated with intellectual disabilities and developmental problems. Patau syndrome is not so common but still it is one of the common trisomy like the down syndrome and Edwards syndrome. Talk of the topics: in the present article we
A karyotype of Patau syndrome- Explained. Read More »
A karyotyping is a process to evaluate chromosomes while a karyotype is a pictorial representation of it. I know it is confusing. People commonly consider karyotyping and karyotype as the same. But let me tell you practically, both techniques are different. For common or non-scientific people both techniques are similar. But as a scientist or
Karyotyping vs Karyotype Read More »