Karyotyping

ISCN- International System for Human Chromosome Nomenclature for Karyotyping

ISCN- International System for Human Chromosome Nomenclature was developed to denote various chromosomal anomalies to make results conclusive universally.  The manual of denotation is based on the outcomes of 1977’s standing committee met in Stockholm.  Karyotyping is a manual process to perform as well as to make and interpret results. Unlike other techniques a vast …

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GTG-Banding (G-bands by Trypsin using Giemsa) for karyotyping

GTG banding also is known as the Giemsa-trypsin-Giemsa banding technique is employed during karyotyping to investigate chromosomes and chromosomal anomalies.  Chromosomal anomalies like structural aberrations or numerical aberrations are commonly encountered using different types of banding techniques. GTG banding, R-banding, NOR-banding and Q- banding are popular techniques used routinely.  However, the GTG banding technique used …

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In which conditions a Karyotyping or a Karyotype Test is preferred?

Karyotyping is a type of genetic test prescribed during the special pregnancy cases to evaluate chromosomes.  A type of genetic test- karyotyping is prescribed during the pregnancy and some cases of having a history of genetic abnormalities.  A karyotyping, popularly known as a karyotype test is usually employed to evaluate chromosomal abnormalities. Unfortunately not so …

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Comparison Between Karyotyping and Microarray

A karyotyping is a conventional cytogenetic technique that visualizes the chromosomes whilst the microarray is a molecular cytogenetic technique that analyses the chromosomes. The cytogenetic techniques rely on the study of chromosomes either structure or numbers. Changes in any of the properties of chromosomes create phenotypic variation.  For instance, we humans have 23 pairs of …

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