Metaphase chromosomes

Importance of Metaphase Chromosomes in Karyotyping

Metaphase chromosomes are often known as metaphase plates or “meta’s” only in technical terms, have significant importance in genetic research, especially in cytogenetics and karyotyping studies.  Techniques like conventional karyotyping, FISH- fluorescence in situ hybridization and SKY highly rely on metaphases. And therefore good, well-separated and sharper metaphases have been the objective first achieved. Although …

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Which Cell Division Phase is Best for Karyotyping?

Which Cell Division Phase is Best for Karyotyping?

Karyotyping is a process of seeing chromosomes in order to know abnormalities related to it. The metaphase chromosomes are most separatable and visible.  Abnormalities in DNA or chromosomes can cause severe mental, physical or developmental disabilities. In order to find out the alteration related to chromosomes, we have to perform the cytogenetic analysis while to …

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