Why only Sodium Heparin Tubes are used to collect Samples for Karyotyping?

Why only Sodium Heparin Tubes are used to collect Samples for Karyotyping?

Karyotyping / By

Sodium heparin is the best anticoagulant agent that prevents coagulation of blood henceforth sodium heparin-containing tubes are commonly used for the sample collection for karyotyping.  A very important procedure in cytogenetics and genetics is sample collection. The quality of results relies on the quality and conditions of the sample. Biological sample collection required special treatment, …

Why only Sodium Heparin Tubes are used to collect Samples for Karyotyping? Read More »

What is Chromosomal Translocation?- Definition, Mechanism and Types

Karyotyping, Karyotyping results / By

When a part of chromosome breaks or is deleted and reinserted at another location on a chromosome is known as a chromosome translocation. Conventional karyotyping is a technique commonly employed to study translocations.  Any sudden change, alteration or undesirable alteration in a gene or chromosome might be harmful to our health. “Mutation” is a common …

What is Chromosomal Translocation?- Definition, Mechanism and Types Read More »

Type of Chromosomes in Normal Karyotype- Metacentric, Acrocentric and Telocentric Chromosomes

Metacentric, Acrocentric and Telocentric Chromosomes

Karyotyping / By

A Cytogenetic technique is known as karyotyping determines the number and structure of chromosomes. Based on the size and shape of chromosomes and location of the centromere it is divided into metacentric, acrocentric, telocentric types.  Two important parts of chromosomes are the arms and the centromere. The location of the centromere varies from chromosome to …

Metacentric, Acrocentric and Telocentric Chromosomes Read More »

Limitations of Karyotyping- What can’t be detected?

Karyotyping / By

“Karyotyping is a technique based on cell culture; employed to detect chromosomal alterations but can’t detect variations at the DNA level.”  Karyotyping is a very traditional, manual and primitive technique, employed in recent times too for the detection of various genetic anomalies. Genetic problems/diseases or anomalies are arisen due to mutations/alterations or variations in either …

Limitations of Karyotyping- What can’t be detected? Read More »

Explaining the whole karyotyping technique and procedure

1 Comment / Karyotyping / By

The process of separating and observing chromosomes is known as karyotyping (collectively) includes cell culture, incubation, cell harvesting and slide preparation.  Genetic techniques are of two types; cytogenetics and molecular genetics. Karyotyping, fluorescence in situ hybridization and chromosome microarray like techniques are categorized in cytogenetic techniques while techniques like Polymerase chain reaction, DNA sequencing and …

Explaining the whole karyotyping technique and procedure Read More »

ISCN- International System for Human Chromosome Nomenclature for Karyotyping

1 Comment / Karyotyping / By

ISCN- International System for Human Chromosome Nomenclature was developed to denote various chromosomal anomalies to make results conclusive universally.  The manual of denotation is based on the outcomes of 1977’s standing committee met in Stockholm.  Karyotyping is a manual process to perform as well as to make and interpret results. Unlike other techniques a vast …

ISCN- International System for Human Chromosome Nomenclature for Karyotyping Read More »

Scroll to Top