The X and Y chromosomes are considered as “sex- chromosomes” or “allosomes” that help in deciding the sex of the fetus. X and Y chromosomes though are popular as sex chromosomes, do a lot more than that for us. In the present article, I will explain to you the structure of the X and Y …
When a part of chromosome breaks or is deleted and reinserted at another location on a chromosome is known as a chromosome translocation. Conventional karyotyping is a technique commonly employed to study translocations. Any sudden change, alteration or undesirable alteration in a gene or chromosome might be harmful to our health. “Mutation” is a common …
What is Chromosomal Translocation?- Definition, Mechanism and Types Read More »
A Cytogenetic technique is known as karyotyping determines the number and structure of chromosomes. Based on the size and shape of chromosomes and location of the centromere it is divided into metacentric, acrocentric, telocentric types. Two important parts of chromosomes are the arms and the centromere. The location of the centromere varies from chromosome to …
Metacentric, Acrocentric and Telocentric Chromosomes Read More »
“Karyotyping is a technique based on cell culture; employed to detect chromosomal alterations but can’t detect variations at the DNA level.” Karyotyping is a very traditional, manual and primitive technique, employed in recent times too for the detection of various genetic anomalies. Genetic problems/diseases or anomalies are arisen due to mutations/alterations or variations in either …
Limitations of Karyotyping- What can’t be detected? Read More »