Image credit: nobelprize.org.
By Dr Tushar Chauhan October 07, 2022
On October 3 2022, the Nobel Prize in Medicine or physiology was announced by the GS of the Nobel Assembly Thomas Perlmann.
Image credit: Wikipedia.
Svante Pääbo won the Nobel Prize in medicine or physiology for his outstanding work retrieving the ancient genomic constituent of extinct hominins.
Image credit: theconversation.com.
He obtained the entire genome sequence of our closest extinct relative Neanderthal. He also obtained the genome sequence of Denisova.
Image credit: independent.co.uk.
Svante Pääbo initially selected the mtDNA for investigations and obtained 61 nucleotide long Neanderthal mtDNA sequence.
Image derived: techexplorist.com (Northwestern University).
The team tested more than 70 bone and tooth samples of Neanderthal during the investigations.
Image credit: washingtonpost.com.
To establish the genetic relationship, the present DNA sequence was compared with 2051 modern-day humans and 59 chimpanzee mtDNA.
Image credit: Canva Images.
He adopted high throughput genome sequencing technique and BLASTn for alignment.
Image credit: NHGRI.
His conclusion suggests that modern-day human DNA is a mixing of Homo sapience with Neanderthal and Denisova during the co-extinction period.
Image credit: washingtonpost.com.