Image credit:Image by kjpargeter on Freepik
By Dr Tushar Chauhan September 25, 2022
Image credit: NHGRI.
The Human Genome Project was conducted to decode the entire genomic sequence of the human genome.
Image credit: NHGRI.
The original project included not only humans but also the genome sequencing of E Coli, drosophila, mouse and yeast.
Image credit:Image by kjpargeter on Freepik
The project was started in October 1990 and was officially completed in April 2003. However, The first draft was published by US and UK in 2000.
Image credit: Wikipedia
Shotgun sequencing was the primary technique for the project. However, the project was completed using Sanger sequencing.
Image credit: NHGRI.
The human genome contains around 3.2 billion base pairs and 20,000 to 30,000 genes.
Image credit: NHGRI.
A huge cohort of the human genome sequences of approx 97% is non-coding, junk or functionally unknown.
Image credit: NHGRI.
The largest human gene is dystrophin which is 2.5Mb in size. Only 2 to 3% portion of the genome contains coding genes.
Image credi: achievement.org
The HG sequencing consortium conducted the project in separate laboratories across 20 different countries including US and UK.
Image credi: achievement.org
Samples were taken from individuals of different races, populations and ethnicity without compromising confidentiality.
Image credit: NHGRI.
The official budget of the entire HGP was 3 billion dollars, meaning it cost roughly one dollar to sequence each nucleotide.
Image credit:Image by kjpargeter on Freepik
HGP provided amazing information regarding human life. Soon after other sequencing projects were initiated to sequence the genome of other organisms.
Video by Andrew Kalanchuk from Pixabay
I hope you like this story. Please share it.